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The chromatographic separation occurs on a reversed-phase C18 column, with the mobile phase composition and flow rates specifically tailored for each neurotransmitter

A sensor cartridge equipped with biosensors for dissolved oxygen and hydrogen ion concentration is positioned above the wells, establishing transient, isolated microenvironments

The CD44 peptide can be further processed by glycosylation and addition of heparin sulfate or chondroitin sulfate [53, 54]

IGF-1 in OA progression In addition to its effects on cartilage metabolism, IGF-1 affects the development of OA in other ways